Drug Name Atarax

Dopamine agonist-induced nausea in parkinsonian patients can be counteracted with D2-receptor antagonists that penetrate poorly into the CNS (e. g. , domperidone, sulpiride).
The effect of these antimetabolites can be reversed by administration of folinic acid (5-formyl- THF, leucovorin, citrovorum factor). Incorporation of false building blocks (3). Unnatural nucleobases (6- mercaptopurine; 5-fluorouracil) or nucleosides with incorrect sugars (cytarabine) act as antimetabolites. They inhibit DNA/RNA synthesis or lead to synthesis of missense nucleic acids.

 

Metronidazole is well absorbed via the enteral route; it is also given i. v. or topically (vaginal insert). Because metronidazole is considered potentially mutagenic, carcinogenic, and teratogenic in the human, it should not be used longer than 10 d, if possible, and be avoided during pregnancy and lactation. Timidazole may be considered equivalent to metronidazole.
Relative deficiency of the von Willebrandt’s factor can be temporarily overcome by the vasopressin anlogue desmopressin, which increases the release of available factor from storage sites. Formation, Activation, and Aggregation of Platelets (B) Platelets originate by budding off from multinucleate precursor cells, the megakaryocytes.